Zogopoulos, V. L., Spaho, K., Ntouka, C., Lappas, G. A., Kyranis, I., Bagos, P., Spandidos D. A., and Michalopoulos, I. (2021). TFBSPred: A functional transcription factor binding site prediction webtool for humans and mice. Int J Epigenetics 1, 9.
Zogopoulos, V.L., Saxami, G., Malatras, A., Angelopoulou, A., Jen, C.H., Duddy, W.J., Daras, G., Hatzopoulos, P., Westhead, D.R., and Michalopoulos, I. (2021). Arabidopsis Coexpression Tool: a tool for gene coexpression analysis in Arabidopsis thaliana. iScience 24, 102848.
Kalogirou, E.M., Thermos, G., Zogopoulos, V., Foutadakis, S., Michalopoulos, I., Agelopoulos, Μ. and Tosios, Κ.Ι. (2021). The immunohistochemical profile of basal cell nevus syndrome–associated and sporadic odontogenic keratocysts: a systematic review and meta-analysis. Clin Oral Invest 25, 3351–3367.
Michalettou, T.D., Michalopoulos, I., Costes, S,V., Hellweg, C.E., Hada, M., and Georgakilas, A.G. (2021). A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression. Life 11, 115.
Gavrielatos, M., Kyriakidis, K., Spandidos, D.A., and Michalopoulos, I. (2021). Benchmarking of next and third generation sequencing technologies and their associated algorithms for de novo genome assembly. Mol Med Rep 23, 251.
The most common approach in transcriptomics (RNA-seq and microarrays) is differential gene expression analysis. Genes identified as differentially expressed may be responsible for phenotype differences between various biological conditions. An alternative approach is gene co-expression analysis, which detects groups of genes with similar expression patterns across unrelated sets of transcriptomic data of the same organism. Co-expressed genes tend to be involved in similar biological processes. This Special Issue will include reviews and research articles on the topic differential gene expression and coexpression. The reviews will provide an overview of the methods available for transcriptomic analysis, while the research articles will provide an in-depth description of each state-of-the-art tool. Please send me an abstract prior to submission to make sure that your work falls within the scope of this Special Issue.
Dr. Ioannis Michalopoulos
Dr. Apostolos Malatras
Malatras, A., Michalopoulos, I., Duguez, S., Butler-Browne, G., Spuler, S., and Duddy, W. J. (2020). MyoMiner: explore gene co-expression in normal and pathological muscle. BMC Med Genomics 13, 67.
Kanakoglou, D.S., Michalettou, T.D., Vasileiou, C., Gioukakis, E., Maneta, D., Kyriakidis, K.V., Georgakilas, A.G., and Michalopoulos, I. (2020). Effects of High-Dose Ionizing Radiation in Human Gene Expression: A Meta-Analysis. Int J Mol Sci 21, 1938.
Angelopoulou, E., Bozi, M., Simitsi, A.M., Koros, C., Antonelou, R., Papagiannakis, N., Maniati, M., Poula, D., Stamelou, M., Vassilatis, D.K., Michalopoulos, I., Geronikolou, S., Scarmeas, N., and Stefanis, L. (2019). The relationship between environmental factors and different Parkinson’s disease subtypes in Greece: Data analysis of the Hellenic Biobank of Parkinson’s disease. Parkinsonism Relat Disord 67, 105–112.